Approaches to identify and characterize microProteins and their potential uses in biotechnology.

Approaches to identify and characterize microProteins and their potential uses in biotechnology. Cell Mol Life Sci. 2018 Apr 18;: Authors: Bhati KK, Blaakmeer A, Paredes EB, Dolde U, Eguen T, Hong SY, Rodrigues V, Straub D, Sun B, Wenkel S Abstract MicroProteins are small proteins that contain a single protein domain and are related to larger, often multi-domain proteins. At the molecular level, microProteins act by interfering with the formation of higher order protein complexes. In the past years, several microProteins have been identified in plants and animals that strongly influence biological processes. Due to their ability to act as dominant regulators in a targeted manner, microProteins have a high potential for biotechnological use. In this review, we present different ways in which microProteins are generated and we elaborate on techniques used to identify and characterize them. Finally, we give an outlook on possible applications in biotechnology. PMID: 29670998 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Tags: Cell Mol Life Sci Source Type: research