Does Pruitt Have a Point about Science?

Scott Pruitt, the Administrator of the U.S. Environmental Protection Agency (EPA), is loathed by most researchers and environmentalists, but he may yet emerge as science ’s unlikely redeemer.Pruitt is one of the least popular people in America. Before coming to DC, he was the attorney general of Oklahoma, where he described himself as “a leading advocate against the EPA’s activist agenda,”— a claim he made good by suing the Agency no fewer than 14 times.But Pruitt — who in public appears reasonable, quietly-spoken and polite — denies having declared war on the environment, only on the EPA’s scientific protocols. The 1970 Clean Air Act requires the agency, when proposing new regulations, use criteria that “accurately reflect the latest scientific knowl edge.”  Governmental skepticism of science has a long pedigree. On launching Medicare on June 15, 1966, LBJ berated the National Institutes of Health for having published lots of papers without their having benefited any patients. Earlier, in his Farewell Address, Eisenhower warned of US public policy becoming “the captive of a scientific-technological elite.” Now Pruitt maintains that skeptical tradition by challenging the EPA’s science—and by extension, much of the way research is performed in the U.S. today.Pruitt hasforbidden the EPA from referencing papers that do not allow free access to their underlying data and methods. Non-scientist...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs

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ConclusionCause or consequences of the renal disease, HT must be properly treated in order to reach the recommended targeted blood pressure values. The time required to take charge the hypertensive stroke determines the prognosis. The challenge is to optimize the health care sector to reduce mortality and sequelae.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Abstract There are no Food and Drug Administration approved pharmacotherapies for methamphetamine (METH) overdose, thus identifying novel drug targets to prevent this devastating adverse event is a public-health imperative. Previous research suggests that serotonin and sigma receptors may contribute to the adverse effects of METH. The present study assessed whether pretreatment with the 5-HT2A receptor antagonist M100907 or the sigma 1 (σ1) receptor antagonist BD 1047 attenuated METH-induced lethality, hyperthermia, convulsions, and seizures. Male Swiss Webster mice received intraperitoneal injections of M10...
Source: Neurotoxicology - Category: Neurology Authors: Tags: Neurotoxicology Source Type: research
Conclusion: Our results suggest that the AT1R mediated hypertensive response to angiotensin II within the NTS in normotensive rats is GABA and NO dependent. Nitric oxide produced within the NTS tonically potentiates local GABA and glutamate release. Introduction The central nervous system network that regulates the level of sympathetic tone and, hence, blood pressure, is located in the brainstem and consists mainly of the rostral ventrolateral medulla (RVLM), the paraventricular nucleus (PVN) of the hypothalamus and the nucleus tractus solitarii (NTS) (Guyenet, 2006). It is well-established that the RVLM, the so-ca...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Geng-Hong Xia1†, Chao You1,2†, Xu-Xuan Gao1, Xiu-Li Zeng1, Jia-Jia Zhu1, Kai-Yu Xu3, Chu-Hong Tan1, Ruo-Ting Xu1, Qi-Heng Wu1, Hong-Wei Zhou3, Yan He4*‡ and Jia Yin1*‡ 1Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China 2Department of Neurology, The First People's Hospital of Zunyi, Zunyi, China 3State Key Laboratory of Organ Failure Research, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China 4Microbiome Medicine Center, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical Univ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Ryan R. Kelly1,2†, Lindsay T. McDonald1,2†, Nathaniel R. Jensen1,2, Sara J. Sidles1,2 and Amanda C. LaRue1,2* 1Research Services, Ralph H. Johnson VA Medical Center, Charleston, SC, United States 2Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, United States The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for os...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
How Bad Is Fentanyl? Fentanyl is an extremely dangerous synthetic opioid. Unlike some other opioids that occur naturally, it is man-made for the purpose of helping aid people suffering from extreme pain. It can be administered for recovery after surgery, during cancer treatments or for recovery after a painful injury. The Drug Enforcement Administration (DEA) classifies fentanyl as a Schedule II controlled substance. This means that it is legal for medical use, however, it has an extremely high potential for abuse and addiction. Understanding Fentanyl Significantly stronger than morphine or oxycodone, Fentanyl can be fatal...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals Drug Rehab Information Drug Treatment Heroin Painkiller Substance Abuse Synthetic fentanyl prescription drug abuse prescription drug addiction prescription drug detox prescription drug use p Source Type: blogs
With the rise in public and professional concern over opioid overdose deaths, a growing emphasis is being placed on using non-opioid analgesics. Nonsteroidal anti-inflammatory drugs, while not new, are garnering new interest as opioid alternatives. Along with demonstrated analgesic efficacy for nociceptive pain, these medications carry significant risks of morbidity and mortality from multiple mechanisms, ranging from hypertension, GI ulcerations, bleeding, kidney injury and cardiovascular acute events.
Source: Pain Management Nursing - Category: Nursing Authors: Source Type: research
Is Cocaine Addictive? According to the Foundation for a Drug Free World, cocaine creates the greatest psychological dependence of any drug, next to methamphetamine. It stimulates key pleasure centers within the brain and causes extremely heightened euphoria. Cocaine addiction, tolerance and dependency builds quickly. If someone uses cocaine, they will not get the same effect as the very next time they do it with the same amount. Understanding Cocaine Cocaine is a white, powdery substance. It creates a high by reacting with the body’s central nervous system, releasing high amounts of dopamine. In turn, this creates en...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Cocaine Drug Rehab Information Drug Treatment Substance Abuse cocaine addiction coke drug addiction drug addiction recovery drug addiction treatment Source Type: blogs
Conclusions: Our results suggest Medicaid expansion benefited a population with unique needs, and that Medicaid expansion could be a valuable tool in addressing the opioid overdose epidemic.
Source: Medical Care - Category: Health Management Tags: Brief Reports Source Type: research
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