Newsdesk North Korea and the Global Fund
The Global Fund's decision to withdraw from North Korea is jeopardising tuberculosis control in the country. Talha Burki reports.
Conclusion: Sarcoidosis cannot be reliably differentiated from tuberculosis based on cytomorphology alone. A combination of clinical features, endosonography, cytology and microbiology is required for accurate diagnosis. PMID: 32476956 [PubMed - in process]
Publication date: Available online 1 June 2020Source: IDCasesAuthor(s): Raguraj Chandradevan, Hironobu Takeda, Tanna Lim, Nidhip Patel
Cuba's Pedro Kourí Tropical Medicine Institute:Battling COVID-19 One Study, One Test, One Patient at a Time. MEDICC Rev. 2020 Jan;22(2):40-44 Authors: Coutin G, Bacallao-Gallestey J, Castellanos-Serra L Abstract This MEDICC Review roundtable brings you specialists from Havana's Pedro Kourí Tropical Medicine Institute (IPK), who are working directly with testing, research and patient care during the COVID-19 pandemic. Founded in 1937 by its namesake, the Institute has gained considerable worldwide prestige. Today, it is a PAHO-WHO Collaborating Center for the Study of Dengue and Its Vector...
ConclusionThe majority of this study cohort had back pain of benign cause. Some red flags were associated with greater risk of serious pathology, others were not. Further evidence regarding red flags and their association with serious pathology is required, to better inform clinical guidelines.
ConclusionsM. vaccae vaccine provided good protection in mice againstM. tuberculosis infection, via a highly complex set of molecular changes. Our findings may provide clue to guide development of more effective vaccine against tuberculosis.
Conditions: TB - Tuberculosis; Patient Satisfaction Intervention: Behavioral: Patient-centred advice on Telephone Consultation in TB Patients: Sponsors: Health Science Center of Xi’an Jiaotong University; Pakistan Institute of Medical Sciences Islamabad Pakistan; District Headquarter Hospital Bannu Pakistan Recruiting
Dalton Trans., 2020, Accepted Manuscript DOI: 10.1039/D0DT01365J, PerspectiveLuiz Gonzaga Fran ça de França Lopes, Edinilton Muniz Carvalho, Eduardo Henrique Silva Sousa Medicinal inorganic chemists have provided many strategies to tackle a myriad of diseases, pushing forward the frontiers of pharmacology. As an example, the fight against tuberculosis (TB), an infectious bacterial... The content of this RSS Feed (c) The Royal Society of Chemistry
Publication date: June 2020Source: Journal of Global Antimicrobial Resistance, Volume 21Author(s): Lebogang Kenaope, Hannetjie Ferreira, Faheem Seedat, Kennedy Otwombe, Neil A. Martinson, Ebrahim Variava
We studied the response of the extracellular matrix of the lungs and liver in mice with BCGinduced granulomatosis (3 months) after inhalation and intraperitoneal administration of liposome-encapsulated dextrazide (LEDZ): a conjugate of oxidized dextran (40 kDa) and isonicotinic acid hydrazide (INH). LEDZ inhalation proved to be more effective in reducing fibrosis severity, both in the lungs and liver. However, the mechanisms of the antifibrotic effect were different: increased degradation and reduced collagen synthesis in the lungs and reduced collagen synthesis and collagen degradation in the liver. This suggest that drug...
Experimental studies of Perchlozone, an antituberculous drug with manifest inhibitory activity towardsMycobacterium tuberculosis andMycobacterium bovis, were carried out. Genotoxicity of Perchlozone was evaluated by the DNA comet method on liver and lung tissues and blood cells after 14-day inhalation exposure of rats. The level of DNA aberrations in response to inhalations of the drug in a concentration of 102.6 ±13.7 mg/m3 increased in lung tissue but not in the blood cells or liver. These results indicated genotoxic activity of antituberculous drug Perchlozone.