Heterogeneity in PPV of RAS Mutations in Cytologically Indeterminate Thyroid Nodules.

CONCLUSION: The PPV of RAS mutations in Bethesda III and IV categories is quite heterogeneous across different studies creating low confidence in the accuracy of a single estimate of PPV. Clinicians must appreciate this wide variability when managing a RAS mutated Cyto-I nodule. Future studies should seek to resolve this unexplained variability. PMID: 29665745 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research