Protective effects of 2-deoxy-D-glucose on nephrotoxicity induced by cyclosporine A in rats.

CONCLUSIONS: 2-DG had obvious protective effect on nephrotoxicity especially with high dose. This protective effect could be related to the reduction of ROS induced by CsA. However, 2-DG had no effect on the expression of RIP3.
PMID: 25197331 [PubMed - in process]

Source: International Journal of Clinical and Experimental Pathology - September 15, 2014 Category: Pathology Authors: Ouyang Z, Cao W, Zhu S, Liu X, Zhong Z, Lai X, Deng H, Jiang S, Wang Y Tags: Int J Clin Exp Pathol Source Type: research