Prokaryotic expression and identification of B- and T-cell combined epitopes of Em95 antigen of Echinococcus multilocularis.

CONCLUSION: Three B- and T-cell combined epitopes were successfully cloned with good immunogenicity and antigenicity. Our data suggest that B- and T-cell combined epitopes predicted from the Em95 antigen may be used for the construction of high-valence vaccines and as targets for prevention of echinococcosis.
PMID: 25197385 [PubMed - in process]

Source: International Journal of Clinical and Experimental Pathology - September 15, 2014 Category: Pathology Authors: Wang H, Zhang F, Ma X, Ma H, Zhu Y, Liu X, Zhu M, Wen H, Ding J Tags: Int J Clin Exp Pathol Source Type: research