002 Tumor-infiltrating CD5+ regulatory B1 cells suppress melanoma tumor immunity via inhibiting cytokine production of tumor-infiltrating CD8+ T cells

In this study, we investigated the role of Bregs in tumor immunity. We used B cell-specific phosphatase and tensin homolog (PTEN)-deficient mice and B16F10 melanoma cells, which were subcutaneously injected into mice.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Adaptive and Auto-Immunity Source Type: research