249 Different prevalence of sensitization against galactose--1,3-galactose between Shimane and Miyagi in Japan

The red meat allergy caused by tick bites are increasing worldwide. It is known that IgE epitope of major red meat allergens is galactose--1,3-galactose ( α-Gal). Thus, the patients with red meat allergy have a high risk to develop anaphylaxis to taking cetuximab that chimera-type monoclonal antineoplastic drug, because it also contains α-Gal, and its cross-reaction. The α-Gal specific IgE (sIgE) test by CAP-fluoro-enzyme immunoassay (FEIA) is one of the most sensitive examination to identify the patients with red meat allergy.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research: Epidemiology of Skin Diseases Source Type: research