354 A comprehensive review of global disease demographics and HLA association in pemphigus vulgaris

Pemphigus vulgaris (PV) is a complex, multifactorial, and polygenic disease, whose exact pathogenesis is difficult to pinpoint. Research aimed at further elucidating associated epidemiologic risk factors is hampered by its rare disease status. Further, a lack of centralization and standardization of available data makes the practical application of this information challenging. We comprehensively reviewed 90 PV articles from 26 different countries for parameters including age, sex, ethnicity, incidence, prevalence, and HLA allele association.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research: Epidemiology of Skin Diseases Source Type: research