1474 Pregnancy improves cutaneous wound healing through enhanced angiogenesis and cell proliferation

Wound healing is an interactive biological process, involving resident cells as well as distant cells issued from bone barrow. The 3 steps of wound healing, namely inflammation, proliferation and remodeling are finely regulated. Our team has recently shown that a peculiar subpopulation of Microchimeric Fetal Cells (MFCs), transferred from the fetus to the mother during pregnancy, specifically migrated to wounded skin and enhanced skin healing though Ccl2/Ccr2 pathway. Pregnancy is characterized by increased hormonal levels and also a high number of circulating fetal cells.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Tissue Regeneration and Wound Healing Source Type: research