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Toddler, 2, is first in UK to have pig skin diaphragm transplant

A LITTLE girl born without a diaphragm has become the first person in Britain to have one built by medics using pig skin. Eve Phillipson, two, had endured two failed operations to rebuild the layer of muscle separating the lungs and the stomach when surgeons made a third and final attempt.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Claire Wineland vowed she wouldn't have a lung transplant, but her decline from cystic fibrosis made her reconsider. Now she's fighting for a chance at survival.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Source Type: research
A 67-year-old, non-Hispanic white male underwent bilateral lung transplantation in 2016 for idiopathic pulmonary fibrosis. The patient had good graft function after transplantation, with a peak forced expiratory volume in 1 second of 2.27 liters. Surveillance bronchoscopy and biopsies done at 1, 3, and 6 months post-transplantation did not show any evidence of acute rejection or infection. He was lost to follow-up until 15 months after transplantation, when he presented with 1 week of dyspnea, cough, and fever.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research
Ischemia-reperfusion injury, a form of sterile inflammation, is the leading risk factor for both short-term mortality following pulmonary transplantation and chronic lung allograft dysfunction. While it is well recognized that neutrophils are critical mediators of acute lung injury, processes that guide their entry into pulmonary tissue are not well understood. Here, we found that CCR2+ classical monocytes are necessary and sufficient for mediating extravasation of neutrophils into pulmonary tissue during ischemia-reperfusion injury following hilar clamping or lung transplantation. The classical monocytes were mobilized fr...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transpl...
Source: BMC Pulmonary Medicine - Category: Respiratory Medicine Authors: Tags: Research article Source Type: research
In people with cystic fibrosis infection with NonTuberculous Mycobacteria is of increasing prevalence. Mycobacterium abscessus complex is of particular concern and has been associated with adverse clinical outcom...
Source: BMC Pulmonary Medicine - Category: Respiratory Medicine Authors: Tags: Research article Source Type: research
Post-thoracotomy pain control in lung transplant recipients is suggested to have a direct impact on short- and long-term outcomes, and is thus a very important component of patient care.1 Thoracic epidural analgesia is considered the gold standard for the post-thoracotomy pain; however, multiple challenges specific to the lung transplant recipients, including hypotension combined with the need for restrictive fluid strategy, the potential need for full systemic heparinization, and timing and coordination of the transplant, make it a less than ideal choice.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Letter to the Editor Source Type: research
The objective of this systematic review was to select articles including chest X-ray or chest CT findings in patients who developed pulmonary tuberculosis following solid organ transplantation (lung, kidney, or liver). The following search terms were used: “ tuberculosis ” ; “ transplants ” ; “ transplantation ” ; “ mycobacterium ” ; and “ lung ” . The databases used in this review were PubMed and the Brazilian Biblioteca Virtual em Sa úde (Virtual Health Library). We selected articles in English, Portuguese, or Spanish, regardless of the year of publicatio...
Source: Jornal Brasileiro de Pneumologia - Category: Respiratory Medicine Source Type: research
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