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Patients with rheumatoid arthritis have a higher prevalence of chronic kidney disease than the general population. This is attributed to nephrotoxic drugs and systemic inflammation. Biologic agents have revolutionized the treatment of rheumatoid arthritis. Sumida and colleagues retrospectively examined a large rheumatoid arthritis cohort to determine whether treatment with biologics has improved kidney outcomes. Using propensity matched patients, the incidence of chronic kidney disease and change in estimated glomerular filtration rate was compared in 4000 patients treated with a biologic agent to 4000 patients who were not treated with a biologic.
Source: Kidney International - Category: Urology & Nephrology Tags: In This Issue Source Type: research