How Medicare Is Going All-In On Diabetes Prevention

We've all heard the rhetoric: Diabetes is preventable.Sometimes, it causes us to roll our eyes, or even get a bit more emotional depending on the context in which that claim is made.   Actually, we've known for a looooong time that type 2 diabetes...
Source: Diabetes Mine - Category: Endocrinology Source Type: blogs

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AbstractPurposeMental well-being among community-dwelling individuals with type 2 diabetes has not been well established. The primary objective was to evaluate the change in the mental well-being of individuals with diabetes. The secondary objective was to evaluate the association between changes in mental well-being and perceived health over 6  months, and any interacting factors in this association.MethodsThis was a prospective, multicenter study. Community-dwelling individuals aged  ≥ 21 years with type 2 diabetes were invited to meet with community pharmacists monthly for 6 months. Indiv...
Source: Quality of Life Research - Category: Health Management Source Type: research
Condition:   Diabetes Mellitus, Type 2 Intervention:   Other: Oral Nutrition Supplement Sponsor:   Nestlé Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: An imbalance in oxidation-reduction processes accompanies obesity. Moreover, inflammatory cytokines and atherosclerotic complications are involved in the obesity process. The obtained results suggest that the studied parameters may be independent prognostic markers preceding the development of cardiovascular and metabolic complications in people afflicted with type II obesity. PMID: 31737129 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Conclusions: On optical coherence tomography angiography, areas of capillary nonperfusion of deep capillary plexus due to macular ischemia are associated with photoreceptor structural abnormalities and retinal sensitivity loss on microperimetry. This highlights that the health status of deep capillary plexus and not only the choroid is important to the oxygen requirements of the photoreceptors in patients with diabetic macular ischemia. Also, the anatomical and functional consequences of these findings might help to explore the efficacy of new therapy into the macular area in clinical practice. PMID: 31737359 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Authors: Nikolajczyk BS, Dawson DR Abstract New strategies are critically needed to counter uncontrolled periodontal infection and inflammation in obesity-associated type 2 diabetes (T2D). However, mechanisms that explain the relationship between periodontitis (PD) and T2D remain poorly understood. Several lines of evidence indicate that destructive immune responses potentiate periodontitis (PD) in T2D. B cells are abundant in periodontal lesions, and our data show that B cells are required for PD in obese/insulin resistant but not lean/normoglycemic mice. In mice and in people, T2D-primed B cells supported Th17 cy...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
In conclusion, long-term studies of NNS consumption are required to draw a firm conclusion abou t the role of NNS consumption on glycaemic control.
Source: Current Atherosclerosis Reports - Category: Cardiology Source Type: research
Conclusions: The higher prevalence of elevated FG and/or T2DM among Roma does not seem to be directly linked to their increased genetic load but rather to their environmental/cultural attributes. Interventions targeting T2DM prevention among Roma should focus on harmful environmental exposures related to their unhealthy lifestyle.
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
Background: Resistin, a cysteine-rich polypeptide encoded by the RETN gene, which plays an important role in many mechanisms in rodent studies, including lipid metabolism, inflammation and insulin resistance. Nevertheless, the relationship between resistin and insulin resistance in humans is under debate. The present study was designed to clarify the correlation between resistin and insulin resistance.Methods: A systematic literature search was performed using PubMed, Embase and Cochrane Library until March 3, 2019 with the keywords “resistin” and “insulin resistance.” Funnel plots and Egger's test ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
AbstractAimsAlthough risk scores to predict type 2 diabetes exist, cost-effectiveness of risk thresholds to target prevention interventions are unknown. We applied cost-effectiveness analysis to identify optimal thresholds of predicted risk to target a low-cost community-based intervention in the USA.MethodsWe used a validated Markov-based type 2 diabetes simulation model to evaluate the lifetime cost-effectiveness of alternative thresholds of diabetes risk. Population characteristics for the model were obtained from NHANES 2001 –2004 and incidence rates and performance of two noninvasive diabetes risk scores (German...
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
Conclusions: Investing in and funding basic and translational childhood diabetes research and encouraging collaborative studies, will bring enormous benefits financially, economically, and socially for the whole of the Middle East region.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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