Epigenetic Aging in Major Depressive Disorder.

CONCLUSIONS: As compared with control subjects, patients with major depression exhibited higher epigenetic aging in blood and brain tissue, suggesting that they are biologically older than their corresponding chronological age. This effect was even more profound in the presence of childhood trauma.
PMID: 29656664 [PubMed - as supplied by publisher]

Source: The American Journal of Psychiatry - April 16, 2018 Category: Psychiatry Authors: Han LKM, Aghajani M, Clark SL, Chan RF, Hattab MW, Shabalin AA, Zhao M, Kumar G, Xie LY, Jansen R, Milaneschi Y, Dean B, Aberg KA, van den Oord EJCG, Penninx BWJH Tags: Am J Psychiatry Source Type: research