Amgen Presents First-Of-Its-Kind Data At AAN Annual Meeting Reinforcing Robust And Consistent Efficacy Of Aimovig ™ (erenumab) For Migraine Patients With Multiple Treatment Failures

The LIBERTY Trial was Conducted in Patients who Have Tried Two to Four Therapies Without Success -- a Uniquely Difficult-to-Treat Population Often Excluded From Migraine Prevention Trials Patients Taking Aimovig had Nearly Three-Fold Higher Odds of Having Their Migraine Days cut by Half or More Compared to Placebo Safety and Tolerability Were Consistent With Results Seen in the Pivotal Clinical Program; Over 97 Percent of Those Taking Aimovig Completed the Double-Blind Treatment Phase Data Selected by the American Academy of Neurology Science Committee as one of the Most Noteworthy Presentations at 2018 Annual Meeting THOUSAND OAKS, Calif., April 17, 2018 /PRNewswire/ -- Amgen (NA...
Source: Amgen News Release - Category: Pharmaceuticals Tags: Uncategorized Source Type: news

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Objectives: This analysis assessed the safety of intravenous immunoglobulin (IVIg) in the treatment of patients with neuroimmunological and immunological disorders in a home-based setting. Methods: Adverse reactions (ARs) were assessed in a retrospective review of 1176 patients receiving 28,677 home-based IVIg infusions between 1996 and 2013. Results: Of 1176 patients, 648 (55.1%) experienced IVIg-related ARs; 536 (45.6%) were mild, 78 (6.6%) moderate, and 34 (2.9%) severe. Thirty-seven (3.1%) patients were hospitalized because of ARs; of these, headache was most common (51.4%). Mean number of ARs per patient incre...
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Original Article Source Type: research
Publication date: Available online 26 May 2018 Source:Journal of Clinical Neuroscience Author(s): Hirotomo Tanaka, Daisuke Yamamoto, Mitsuru Ikeda, Masashi Morikawa, Kayo Ueda, Kazuhiro Tanaka, Takashi Sasayama, Eiji Kohmura The 2007 World Health Organization Classification of Tumors of the Central Nervous System (CNS) categorized embryonal tumors of the CNS into three classes: medulloblastoma, CNS primitive neuroectodermal tumor, and atypical teratoid/rhabdoid tumor. Due to the lack of specific histological features, it was sometimes difficult to accurately differentiate CNS embryonal tumors pathologically. Here, we repo...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
ConclusionsThe treating physician should consider the rare but very treatable condition of rickettsial infection as a differential diagnosis in the etiological diagnostic workup of patients presenting with severe purpuric and hemorrhagic rash with fever.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
PMID: 29784185 [PubMed - in process]
Source: Canadian Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Can J Ophthalmol Source Type: research
Conditions:   Acute Pain;   Headache;   Musculoskeletal Pain Interventions:   Behavioral: Usual Care/Guideline;   Behavioral: Opioid Justification;   Behavioral: Provider Comparison Sponsors:   University of Pittsburgh;   Patient-Centered Outcomes Research Institute;   Geisinger Clinic;   University of Utah Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Migraine;   Migraine With Aura;   Migraine; Status Intervention:   Sponsor:   University Hospital Inselspital, Berne Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Acute Pain;   Headache;   Musculoskeletal Pain Interventions:   Behavioral: Usual Care/Guideline;   Behavioral: Opioid Justification;   Behavioral: Provider Comparison Sponsors:   University of Pittsburgh;   Patient-Centered Outcomes Research Institute;   Geisinger Clinic;   University of Utah Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Migraine;   Migraine With Aura;   Migraine; Status Intervention:   Sponsor:   University Hospital Inselspital, Berne Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
For most of us, springtime marks the return of life to a dreary landscape, bringing birdsong, trees in bud, and daffodils in bloom. But if you work for the Centers for Disease Control and Prevention (CDC), the coming of spring means the return of nasty diseases spread by ticks and mosquitoes. The killjoys at CDC celebrated the end of winter with a bummer of a paper showing that infections spread by ticks doubled in the United States from 2004 to 2016. (Tick populations have exploded in recent decades, perhaps due to climate change and loss of biodiversity.) Lyme disease The most common infection spread by ticks in the US i...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infectious diseases Source Type: blogs
Conclusions—In a large, heterogeneous multistate cohort, probable misdiagnosis of CVT occurred in 1 of 30 patients but was not associated with the adverse clinical outcomes included in our study.
Source: Stroke - Category: Neurology Authors: Tags: Quality and Outcomes, Thrombosis Brief Reports Source Type: research
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