This Sleep Pattern Linked to Alzheimer ’s Disease
Usually neurons shrink while we sleep, allowing waste products to clear. Articles marked (S) are for subscribers only. → Subscribe for just $4 per month. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: NEW: Accept Yourself: Self-Acceptance Practices For Emotional Healing Activate: How To Find Joy Again By Changing What You Do The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything
Background: The circadian timing system or circadian clock plays a crucial role in many biological processes, such as the sleep-wake cycle, hormone secretion, cardiovascular health, glucose homeostasis, and body temperature regulation. Energy balance is also one of the most important cornerstones of metabolic processes, whereas energy imbalance is associated with many diseases (i.e., obesity, diabetes, cardiovascular disease). Circadian clock is the main regulator of metabolism, and this analysis provides an overview of the bidirectional effect of circadian rhythm on metabolic processes and energy balance.Summary: The circ...
Publication date: Available online 23 April 2019Source: Epilepsy &BehaviorAuthor(s): Maria R. Lopez, Steven C. Schachter, Andres M. KannerAbstractPatients with epilepsy (PWE) have a significantly higher prevalence of psychiatric comorbid disorders involving depression, anxiety, psychotic, and attention-deficit disorders compared with the general population or patients with other chronic medical conditions. Currently, there is no systematic approach in the evaluation and management of psychiatric comorbidities in these patients. In addition, neurologists are not trained to recognize these disorders, and consequently, th...
Publication date: May–June 2019Source: Brain Stimulation, Volume 12, Issue 3Author(s): Brice V. McConnell, Rini I. Kaplan, Peter D. Teale, Eugene Kronberg, Josiane L. Broussard, Jacob R. Guzetti, Stefan H. Sillau, A. Ranjitha Dhanasekaran, Benzi M. Kluger, Brian D. Berman
Conclusions: The surrogates were more agreeable to considering assisted dying in the setting of advanced dementia than the physicians, and about half of the participants in both groups reported CDS to be an appropriate option for this population.Neurodegener Dis
Conclusions: OBT-A seems to have an effect on central sensitization, expressed by allodynia. This action could be exerted by modulating nociceptive transmission, and reducing the global burden of migraine. Patients with more severe allodynia display a limited long-term effect on headache frequency. The modulation of central sensitization could reduce migraine disability, in spite of the persistence of frequent headache.Eur Neurol 2019;81:37 –46
Conclusions: This cutoff value can be applied clinically to evaluate brain atrophy in HD. Our method is advantageous because it is simple and can be implemented easily in daily clinical practice.Eur Neurol 2019;81:13 –18
AliveCor is giving consumers a chance to understand their heart (beats) a whole better through a pair of new indications. The Mountain View, CA-based company said its KardiaMobile ECG is now cleared for the detection of BradyCardia and TachyCardia. Previously, AliveCor had a nod from FDA for KardiaMobile to detect Atrial Fibrillation (AFib) and Normal Sinus Rhythm. The Mountain View, CA-based company said the new indications make it the only consumer-cleared device with the ability to detect the three most common heart arrhythmias. "No other consumer ECG device in the world, can tell you more about your heart than Kar...
Longitudinal plasma neurofilament light (NfL) levels are associated with neurodegeneration in Alzheimer disease, researchers report.Reuters Health Information
Sleep can help to clear the brain of toxic substances that lead to Alzheimer's disease. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do