Paraneoplastic glomerulopathies associated with hematologic malignancies.

We present three cases of paraneoplastic NS associated with hematological malignancies. Early diagnosis and treatment can alter prognosis of these patients. Paraneoplastic syndromes would remit only with proper treatment of the neoplasia. PMID: 29657219 [PubMed - in process]
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research

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Conclusions: The results of our study demonstrated that DJ stent removal within 14 days did not reduce the risk of UTI when compared to stent removal after 14 days. Similar effects on complication rates for ureteral stenting for these 2 removal periods were observed. PMID: 30899293 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Authors: Martins RM, Teodoro JS, Furtado E, Rolo AP, Palmeira CM, Tralhão JG Abstract Background/Aims: We measured changes in mitochondrial function and bioenergetics that occur during ischemia/ reperfusion in fresh liver samples of patients undergoing liver transplantation. These variations correlated with markers of liver function and clinical outcome. Ischemia/reperfusion injury related to liver transplantation affects mitochondrial function and bioenergetics. Experimental studies were conducted to identify the role of bioenergetics and mitochondrial dysfunction. To the best of our knowledge, no investiga...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
CONCLUSION: Compared with a laboratory-based assay, the point-of-care assay that utilizes GTS-7000® is accurate and rapid despite being slightly more expensive. Further trials using this assay are warranted.
. PMID: 30900981 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research
Publication date: Available online 23 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Aqsa Habib, Mansoureh Nazrai Vishkaei, Muhammad Adnan Iqbal, Haq Nawaz Bhatti, M.B. Khadeer Ahmed, A.M.S. Abdul MajidAbstractThe promising biomedical applications of silver complexes stimulated the researchers to test these compounds against cancer. The present research work was designed to achieve this goal. In this work, a series of 5-methyl benzimidazole based N-Heterocyclic carbene ligands and respective silver(I) complexes were synthesized and tested on cancer cell lines to assess their anticancer activity. Unsymmetrica...
Source: Journal of Saudi Chemical Society - Category: Chemistry Source Type: research
Publication date: Available online 23 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Nesrine Amiri, Sahar Nouir, Melek Hajji, Thierry Roisnel, Taha Guerfel, Gérard Simonneaux, Habib NasriAbstractA new bioactive material of cobalt(II) with 5,10,15,20-tetrakis[4 (benzoyloxy)phenyl] porphyrin (TPBP) and bpy ligands ([CoII(TPBP)(bpy)2] 1) has been synthesised and characterized by Single-crystal X-ray diffraction (SCXRD), spectroscopic methods and quantum-chemistry calculations. In the crystalline structures of six coordinated Co(II) [CoII(TPBP)(bpy)2] 1, linear 1D polymeric chains were observed in which a...
Source: Journal of Saudi Chemical Society - Category: Chemistry Source Type: research
This study is the first to identify a Korean MCPyV strain in whole-blood samples from Korean patients with kidney disease and healthy individuals.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
This study was funded in part by the National Institutes of Health (NIH) through MD Anderson's Cancer Center Support Grant ( CA016672).
Source: The Lancet Haematology - Category: Hematology Source Type: research
Publication date: Available online 22 March 2019Source: Pharmacological ResearchAuthor(s): Saeideh Hajighasemi, Armita Mahdavi Gorabi, Vanessa Bianconi, Matteo Pirro, Maciej Banach, Hossein Ahmadi tafti, Željko Reiner, Amirhossein SahebkarAbstractFamilial hypercholesterolemia (FH) is a genetic autosomal dominant disorder caused by an impaired receptor-mediated low-density lipoprotein (LDL) removal from the circulation, mainly due to disruptive autosomal co-dominant mutations in the LDL receptor (LDLr) gene, but also less frequently in the apolipoprotein B100 (APOB) and proprotein convertase subtilisin/kexin type 9 (PCSK9)...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Discussion: Incomplete septal cirrhosis is an uncommon cause of non-cirrhotic portal hypertension. Its definition is not well known, morphological and pathophysiological. We have not found published cases of post-RT ascites secondary to this pathology, described as possibly associated with drugs, immune alterations, infections, hypercoagulability and genetic predisposition. PMID: 30897191 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Publication date: Available online 23 March 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Hiroshi Ureshino, Kazuharu Kamachi, Shinya KimuraAbstractMogamulizumab, a defucosylated humanized monoclonal antibody against C–C chemokine receptor 4 (CCR4), has been approved for the treatment of relapsed adult T-cell leukemia/lymphoma (ATL). Compared with conventional chemotherapy, mogamulizumab monotherapy displayed more effecacy in relapsed ATL making mogamulizumab a promising therapeutic agent. However, mogamulizumab could increase graft-versus-host disease, resulting in poor survival outcome in allogenic st...
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
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