Sunitinib therapy as a cause of diffuse digestive tract hemorrhage in end-stage renal disease patient.
Sunitinib therapy as a cause of diffuse digestive tract hemorrhage in end-stage renal disease patient. Saudi J Kidney Dis Transpl. 2018 Mar-Apr;29(2):483-484 Authors: Taki Y, Imai N, Kojima S, Kaneshiro N, Shibagaki Y PMID: 29657229 [PubMed - in process]
This article describes the genetics of NS/SRNS in childhood and also gives a narrative review of the challenges and opportunities for molecular testing among children with SRNS in Nigeria. For these children to benefit from genetic diagnosis, Nigeria must aspire to have and develop the manpower and infrastructure required for medical genetics and genomic medicine, leveraging on her existing experiences in genomic medicine. Concerted efforts can be put in place to increase the number of enrollees in Nigeria's National Health Insurance Scheme (NHIS). The scope of the NHIS can be expanded to cater for the expensive bill of ge...
In this study, we pursued a candidate gene approach to measure WNT pathway genes in residual clinical FFPE biopsies with and without MVI. We focused on the WNT pathway because of previous translational studies that implicated this pathway in chronic renal allograft injury as well as vascular injury in native chronic kidney disease.
Publication date: Available online 13 June 2019Source: IDCasesAuthor(s): Jose Armando Gonzales Zamora, Yogeeta Varadarajalu
(ERA-EDTA) As chronic kidney disease (CKD) progresses, the kidneys become less able to maintain a healthy balance of acids in the body. To maintain healthy acid levels, people with CKD are treated with alkaline substances such as sodium bicarbonate, also commonly used to neutralize heartburn and indigestion. The UBI study shows that sodium bicarbonate halves the risk of kidney disease progression, the likelihood of needing dialysis or transplantation) and overall mortality in people with CKD .
(ERA-EDTA) While a kidney transplant can restore healthy kidney function, recipients remain at increased risk of fractures, heart disease, diabetes and some cancers. The VITALE study shows that, compared with currently recommended doses, high doses of oral vitamin D? (cholecalciferol) lower the risk of fractures, but have no effect on the risks of heart disease, diabetes or cancer after a kidney transplant .
PMID: 31197384 [PubMed - as supplied by publisher]
Publication date: Available online 13 June 2019Source: Journal de Mycologie MédicaleAuthor(s): P. Pavone, A. Oliva, G. Raponi, F. Pugliese, S. Martelli, P. Celli, F. Sacco, V. Vullo, C.M. Mastroianni, G. RussoAbstractSaprochaete clavata and Saprochaete capitata are closely related fungal species (family Dipodascaceae, order Saccharomycetales) that are rarely involved in the etiology of systemic infections in humans. In recent years, these yeasts are emerging as cause of life-threatening infections in patients with severe neutropenia and haematological malignancies. Infections by these fungi have been reported mostly...
Switching standard compression stockings for muscle-pump activators (MPAs) on a kidney-transplantation patient's legs cuts hospitalization time and improves short-term outcomes, a new randomized trial suggests.Reuters Health Information
CONCLUSIONS We preliminarily demonstrated that miR-30c-5p agomir might decrease renal I/R through transformation of M1 macrophages to M2 macrophages and resulted in changes in inflammatory cytokines. PMID: 31185006 [PubMed - in process]
(Johns Hopkins Medicine) Long-term hemodialysis is a lifesaver for approximately half a million patients in the United States with kidney failure (also known as end-stage renal disease, or ESRD) who are either waiting on or unsuitable for a kidney transplant. But before the external machinery can take over the function of the kidneys -- filtering and cleansing wastes from the blood -- a minor surgical procedure is needed to create a stable, functional and reusable access to the circulatory system, usually through blood vessels in the arm.