Using biology to guide the treatment of sarcomas and aggressive connective-tissue tumours

Using biology to guide the treatment of sarcomas and aggressive connective-tissue tumoursUsing biology to guide the treatment of sarcomas and aggressive connective-tissue tumours, Published online: 17 April 2018; doi:10.1038/s41571-018-0012-4Patients with sarcomas have historically been treated with surgery and/or chemotherapy, although the outcomes achieved with these approaches, especially in advanced-stage disease, are often disappointing. In this Review, the authors describe the opportunities created by selective use of targeted therapies on the basis of the biological characteristics of individual tumours.
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Source Type: research