IJERPH, Vol. 15, Pages 771: Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder

Conclusions: A pheno-biotype of depression more, or less likely, to benefit with ketamine treatment is far from complete. Notwithstanding, metabolic-inflammatory alterations are emerging as possible pretreatment response predictors of depressive symptom improvement, most notably being cognitive impairment. Sophisticated data-driven computational methods that are iterative and agnostic are more likely to provide actionable baseline pretreatment predictive information.

Source: International Journal of Environmental Research and Public Health - April 17, 2018 Category: Environmental Health Authors: Carola Rong Caroline Park Joshua D. Rosenblat Mehala Subramaniapillai Hannah Zuckerman Dominika Fus Yena L. Lee Zihang Pan Elisa Brietzke Rodrigo B. Mansur Danielle S. Cha Leanna M. W. Lui Roger S. McIntyre Tags: Article Source Type: research