The Beneficence of Hope: Findings from a Qualitative Study with Gout and Diabetes Patients

AbstractThis paper explores the importance of hope as a determining factor for patients to participate in first-in-human trials for synthetic biology therapies. This paper focuses on different aspects of hope in the context of human health and well-being and explores the varieties of hope expressed by patients. The research findings are based on interview data collected from stable gout and diabetes patients. Three concepts of hope have emerged from the interviews: hope as certainty (H1); hope as reflective uncertainty (H2); hope as self-therapy (H3). The purpose of the paper is twofold. First, it aims to underline the significance of hope in patients ’ medical decision-making, as well as the beneficence of hope for patients’ well-being, and for progress in research. Second, it shows how philosophical investigations—in particular Descartes—explore the phenomenon of hope and provide medical empirical research with profitable insights and t ools.
Source: Journal of Bioethical Inquiry - Category: Medical Ethics Source Type: research

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ConclusionsOur results suggest that metformin users are more likely to initiate preventive therapies and engage in other healthy behaviors. Failure to account for these behaviours may introduce healthy user bias into studies evaluating the effect of oral antidiabetic therapies.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Amyloid light-chain (AL) amyloidosis is associated with plasma cell disorder and monoclonal light chains. This type of amyloidosis is the prominent type involving the gastrointestinal tract. Monoclonal gammopathy of undetermined significance (MGUS) is the most common plasma cell disorder and a known precursor of more serious diseases. A 72-year-old male was treated for high blood pressure, diabetes, and gout at the clinic of a private physician. Due to a positive fecal occult blood test discovered during colon cancer screening, he underwent colonoscopy and was diagnosed with adenomatous polyps by biopsies. Two months later...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
Abstract OBJECTIVE: Febuxostat has superior renal safety to allopurinol, but data on its hepatic safety are limited. Thus we compared the hepatotoxicity of febuxostat and allopurinol, and the clinical factors associated with hepatotoxicity, in patients with gout and fatty liver disease (FLD). METHODS: We included gout patients treated with allopurinol or febuxostat who were diagnosed with fatty liver based on ultrasonography or computed tomography. Hepatotoxicity was defined as follows: (1) elevation of aspartate aminotransferase (AST)/alanine aminotransferase (ALT) at least 3× the upper limit of normal...
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
(Natural News) Vitamin C has been reported to prevent and treat infection, heart disease, diabetes, and cancer. Another study has shown that it can also prevent gout. Gout is one of the most common types of arthritis that causes severe pain, swelling, and stiffness in a joint, typically affecting the joint in the big toe....
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ConclusionsThenar atrophy and sensory loss were highly specific in CTS but had limited value in early detection. Due to their low specificity, provocative tests do not appear sufficient enough to establish a definite CTS diagnosis. Only Durkan’s test could possibly be considered initially as it has more balanced values. Diabetes, obesity, rheumatoid arthritis, hypothyroidism and gout significantly increase the risk of CTS.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
When I was a kid, grasshoppers were everywhere. I walked through a field every day to get to school and grasshoppers were everywhere, jumping back and forth across my path, frequently banging off my legs. At night in summer, the backyard was filled with fireflies that we’d chase and capture in jars to watch up close. And there were butterflies of many colors and varieties everywhere, flitting from flower to flower. Today, I don’t see any grasshoppers. In fact, I haven’t seen one in over 40 years. I saw one—just one—firefly this past summer in my backyard. And I can count the number of butterie...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Agribusiness bowel flora Inflammation microbiota prebiotic probiotic wheat belly Source Type: blogs
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Source: OnMedica Latest News - Category: UK Health Source Type: news
hunpeng Wan Medicinal plants have served humans since prehistoric times to treat various ailments. Both developed and underdeveloped countries rely on traditional systems of medication using natural sources from plants. Phyllanthus is one of the largest genus in the family Phyllanthaceae, comprising over 700 well known species cosmopolitan in distribution mainly in the tropics and subtropics. Phyllanthus species are being in constant used in traditional medications to cure an array of human diseases (constipation, inhalation related, arthritis, loss of appetite, injuries, conjunctivitis, diarrhoea, running nose, common...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
Recent  decreasing  trends  of  exposure  to  PCDDs/PCDFs/dioxin-like  PCBs  in  general  populations,  and  associations with  diabetes,  metabolic  syndrome,  and  gout/hyperuricemia. J Med Invest. 2018;65(3.4):151-161 Authors: Kokichi A Abstract The author reviewed recent reports about the blood levels and dietary intake of polychlorinated dibenzo-p-dioxins (PCDDs)/furans (PCDFs)/dioxin-like polychlorinated biphenyls (DL-PCBs) to investigate the trends of dioxin exposure, and epidemiologic studies on the association...
Source: Journal of Medical Investigation - Category: General Medicine Tags: J Med Invest Source Type: research
Source: Clinical and Experimental Nephrology - Category: Urology & Nephrology Source Type: research
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