The Beneficence of Hope: Findings from a Qualitative Study with Gout and Diabetes Patients

AbstractThis paper explores the importance of hope as a determining factor for patients to participate in first-in-human trials for synthetic biology therapies. This paper focuses on different aspects of hope in the context of human health and well-being and explores the varieties of hope expressed by patients. The research findings are based on interview data collected from stable gout and diabetes patients. Three concepts of hope have emerged from the interviews: hope as certainty (H1); hope as reflective uncertainty (H2); hope as self-therapy (H3). The purpose of the paper is twofold. First, it aims to underline the significance of hope in patients ’ medical decision-making, as well as the beneficence of hope for patients’ well-being, and for progress in research. Second, it shows how philosophical investigations—in particular Descartes—explore the phenomenon of hope and provide medical empirical research with profitable insights and t ools.
Source: Journal of Bioethical Inquiry - Category: Medical Ethics Source Type: research

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Abstract Xanthine oxidase (XO) can catalyze xanthine to uric acid and has also been linked with the extension of some serious diseases such as cancer, gout, diabetes and so on. Thymol is a part of diet in the form of spices. Due to the high antioxidant activity, its inhibitory effect on XO was studied in the present work. XO organized in four redox domains which exhibiting electrochemical signals. Therefore, voltammetric methods can be used to obtain the valuable information about the action mechanism of thymol on XO. However, there are extreme complexities in these biological sample matrices which make the deeper...
Source: International Journal of Biological Macromolecules - Category: Biochemistry Authors: Tags: Int J Biol Macromol Source Type: research
Coffee is among the most popular beverages ever, enjoyed by millions of people worldwide each day. Estimates suggest that Americans consumed 3.4 billion pounds of coffee last year. When it comes to its health effects, coffee is also among the best studied beverages. How much is too much? Does coffee cause cancer? What is behind the proposed new warning label for coffee? Fortunately, the news on coffee is mostly good. This includes a recent study that found coffee drinkers live longer, a conclusion that held up even for heavy coffee consumption (eight or more cups of coffee each day), and regardless of whether the coffee wa...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Healthy Eating Source Type: blogs
Publication date: June 2018Source: American Journal of Kidney Diseases, Volume 71, Issue 6Author(s): Richard J. Johnson, George L. Bakris, Claudio Borghi, Michel B. Chonchol, David Feldman, Miguel A. Lanaspa, Tony R. Merriman, Orson W. Moe, David B. Mount, Laura Gabriella Sanchez Lozada, Eli Stahl, Daniel E. Weiner, Glenn M. ChertowUrate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome, but its relationship to kidney disease, cardiovascular disease, and diabetes remains controversial. A scientific workshop organized by the National Kidney Foundation was held in September 2016 to review c...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: Available online 2 July 2018Source: Beni-Suef University Journal of Basic and Applied SciencesAuthor(s): Abdulwakeel Ayokun-nun Ajao, Ojo Michael Oseni, Olaniran Temitope Oladipo, Yusuf Agbomekhe Adams, Yusuf Ola Mukaila, Abdulwadud Abiodun AjaoAbstractClerodendrum volubile is an underutilized vegetable native to West Africa most especially Nigeria. The plant is used traditionally in the treatment of arthritis, diabetes, dropsy, gout rheumatism, dropsy, swellings, oedema, and analgesic. The ethnopharmacological potential of C. volubile through its phytochemistry, biological activities, and proximate analy...
Source: Beni Suef University Journal of Basic and Applied Sciences - Category: Science Source Type: research
Publication date: May 2018Source: Joint Bone Spine, Volume 85, Issue 3Author(s): Milka Maravic, Natalia Hincapie, Simon Pilet, René-Marc Flipo, Frédéric LiotéAbstractObjectiveTo describe the characteristics and management of patients with gout in France during the year 2014.MethodsData were obtained from a computerized observational longitudinal patient database of a representative sample of 1200 general practitioners. Patients on urate-lowering treatment and/or colchicine were described by demographics and comorbidities, quality of management indicators (serum uric acid and renal function testi...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 28 June 2018Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Marie Doualla-Bija, Yonathan Lobe Batchama, Jude Moutchia-Suh, Vicky Joceline Ama Moor, Félicité Kamdem, Fernando Kemta Lekpa, Henry Luma NammeAbstractBackgroundEvidence from epidemiological studies suggests an important association between gout and the metabolic syndrome (MetS). However, to the best of our knowledge, prevalence of metabolic syndrome in gout has not been reported in sub-Saharan African (SSA) settings.ObjectivesThe aim of this study was to determine the prevalence a...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 2 July 2018Source: Beni-Suef University Journal of Basic and Applied SciencesAuthor(s): Abdulwakeel Ayokun-nun Ajao, Michael Ojo Oseni, Olaniran Temitope Oladipo, Yusuf Agbomekhe Adams, Yusuf Ola Mukaila, Abdulwadud Abiodun AjaoAbstractClerodendrum volubile is an underutilized vegetable native to West Africa most especially Nigeria. The plant is used traditionally in the treatment of arthritis, diabetes, dropsy, gout rheumatism, dropsy, swellings, oedema, and analgesic. The ethnopharmacological potential of C. volubile through its phytochemistry, biological activities, and proximate analy...
Source: Beni Suef University Journal of Basic and Applied Sciences - Category: Science Source Type: research
Publication date: June 2018Source: American Journal of Kidney Diseases, Volume 71, Issue 6Author(s): Richard J. Johnson, George L. Bakris, Claudio Borghi, Michel B. Chonchol, David Feldman, Miguel A. Lanaspa, Tony R. Merriman, Orson W. Moe, David B. Mount, Laura Gabriella Sanchez Lozada, Eli Stahl, Daniel E. Weiner, Glenn M. ChertowUrate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome, but its relationship to kidney disease, cardiovascular disease, and diabetes remains controversial. A scientific workshop organized by the National Kidney Foundation was held in September 2016 to review c...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Publication date: May 2018Source: Joint Bone Spine, Volume 85, Issue 3Author(s): Milka Maravic, Natalia Hincapie, Simon Pilet, René-Marc Flipo, Frédéric LiotéAbstractObjectiveTo describe the characteristics and management of patients with gout in France during the year 2014.MethodsData were obtained from a computerized observational longitudinal patient database of a representative sample of 1200 general practitioners. Patients on urate-lowering treatment and/or colchicine were described by demographics and comorbidities, quality of management indicators (serum uric acid and renal function testi...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 28 June 2018Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Marie Doualla-Bija, Yonathan Lobe Batchama, Jude Moutchia-Suh, Vicky Joceline Ama Moor, Félicité Kamdem, Fernando Kemta Lekpa, Henry Luma NammeAbstractBackgroundEvidence from epidemiological studies suggests an important association between gout and the metabolic syndrome (MetS). However, to the best of our knowledge, prevalence of metabolic syndrome in gout has not been reported in sub-Saharan African (SSA) settings.ObjectivesThe aim of this study was to determine the prevalence a...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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