Don ’t Ditch the Coffee Over Cancer Risk News
If you drink a moderate amount of coffee now, there’s no good reason to stop. For those who don’t drink coffee, don’t expect your doctor to recommend that you start.
This study investigated the presence of Streptococci, Staphylococci, aerobic gram negative bacteria (AGNB), Candida and bacterial endotoxins in the oral cavities of patients receiving chemo- and/or radiotherapy for cancer.MethodsSamples of oral cavity rinse were collected from 100 patients on cancer treatment and 70 healthy individuals. Demographic and clinical data were recorded. Samples were cultured onto various agar plates for qualitative and quantitative analysis and tested for the presence of endotoxin. Results were analysed using the Mann-Whitney and chi-square tests.ResultsIn cancer patients, S. aureus counts were ...
AbstractLow molecular weight heparins (LMWHs) are considered the standard of care for the treatment of venous thromboembolism (VTE) associated with cancer. We conducted a meta-analysis to evaluate the safety and efficacy of direct oral anticoagulants (DOACs) in patients with cancer. We systematically searched Medline for potential randomized-control clinical trials (RCTs) and post-hoc analyses. For each study, data on recurrent VTE, major or clinically relevant non-major bleeding (CRNMB), and major bleeding (MB) were extracted. Initially, a total of 1395 citations were identified. Eight studies met our eligibility criteria...
ConclusionsBilateral mandibular osteoradionecrosis can be managed with virtual surgical planning, and the defects can be reconstructed using 2 separate flaps prepared from a single fibula.
Death rates from both diseases have risen sharply, particularly among young adults over the last decade. A possible villain: the Great Recession.
Rethinking Successful Care for Pancreatic Cancer: Therapeutic Sequencing, Innovative Strategies, and Patient Perspectives on Disease Management
Publication date: Available online 18 July 2018Source: Pharmacological ResearchAuthor(s): Nathan Griffin, Sam Faulkner, Phillip Jobling, Hubert HondermarckAbstractNerve outgrowth in the tumor microenvironment (tumor neurogenesis) has recently been shown to be essential for cancer progression and the concept of nerve dependence is emerging in oncology. Neurotrophins such as nerve growth factor (NGF) have long been identified as drivers of neurogenesis during development and regeneration, but intriguingly they were also known to be expressed in human tumors where they can stimulate cancer cell growth. Recent findings have un...
(MedPage Today) -- Dutch study reports increases in multiple types of tumors
ConclusionsThese findings support the hypothesis that histologic subtypes of RCC possess distinct etiologic pathways, with obesity important for the development of clear cell and, possibly, chromophobe RCC, but not papillary RCC.
TURBT with fluorescent light source using oral 5-ALA is well tolerated in non –muscle-invasive bladder cancer.
In a phase I trial, this first-in-class novel drug yielded a 71% response rate in very high expressers of PD-L1 treated at 1,200 mg every 2 weeks.