Investigation of miR-136-5p key target genes and pathways in lung squamous cell cancer based on TCGA database and bioinformatics analysis.

CONCLUSIONS: Downregulated miR-136-5p may target UGT1A7 and ADH7 and participate in ascorbate and aldarate metabolism, pentose and glucuronate interconversions, and retinol metabolism. High expression of UGT1A7 and ADH7 may indicate better prognosis of LUSC patients.
PMID: 29650443 [PubMed - as supplied by publisher]

Source: Pathology, Research and Practice - April 5, 2018 Category: Pathology Authors: Xie ZC, Li TT, Gan BL, Gao X, Gao L, Chen G, Hu XH Tags: Pathol Res Pract Source Type: research