Diabetes type 2 - five food swaps to lower your blood sugar
DIABETES type 2 symptoms can include weight loss, fatigue and feeling constantly thirsty. Making the right diet choices is important for high blood sugar patients. Add these five foods to your meal plan to reduce signs of the condition.
Psoriasis is an independent risk-factor for development of insulin resistance and Type 2 diabetes (T2D). Here we used the imiquimod (IMQ) mouse model of psoriasis to investigate the effects of skin inflammation on insulin sensitivity and beta-cell function. To induce skin inflammation in mice, 75 mg of 5% IMQ cream (Aldara, Meda Pharma) was applied topically to a shaved dorsal region for 4 consecutive days (n = 3-8). Control mice were treated with Vaseline cream. On the fifth day, mice were either fasted for glucose tolerance testing, or sacrificed in the fed state with blood and tissues collected for analysis (qPCR, ELISA and IF).
Non-healing foot ulcers develop in 10-25% of type 2 diabetics. We have previously shown that reduction in ganglioside GM3 by GM3 synthase (GM3S) gene knockdown or topically applied GM3S siRNA nanoconstructs normalizes wound healing in diet-induced obese (DIO) diabetic mice. The mechanism is reversal of IGF-1 and EGF receptor resistance, leading to accelerated keratinocyte migration and normal cutaneous innervation. A small molecule inhibitor of glucosylceramide synthase (GCSI) also reduces GM3 and, given GCSI's small size, could be moved towards clinical trials of topical application should it replicate the ameliorative ef...
DIABETES type 2 symptoms can be weight loss, frequent urination and fatigue. The disease often develops in later life as the body becomes less sensitive to insulin, the hormone that helps to regulate blood sugar levels. It is often treated through medication and lifestyle changes.
PHILIP Bell, 73, takes at least seven medications a day for illnesses which could kill him at any moment. The married former healthcare worker from Anglesey, North Wales, has atrial fibrillation, osteoarthritis, Type 2 diabetes, an enlarged prostate, sleep apnoea and hearing loss.
Publication date: Available online 16 April 2018 Source:The Lancet Diabetes & Endocrinology Author(s): Angus Forbes, Trevor Murrells, Henrietta Mulnier, Alan J Sinclair Background Glycaemic targets for older people have been revised in recent years because of concern that more stringent targets are associated with increased mortality. We aimed to investigate the association between glycaemic control (mean HbA1c) and variability (variability of HbA1c over time) and mortality in older people with diabetes. Methods We did a 5-year retrospective cohort study using The Health Improvement Network database, which includes da...
(Natural News) Your environment defines you. People absorb the habits and ways of the place they’re living in. That’s what a new UT Southwestern study proved once more when researchers from the premier academic medical center’s Human Nutrition team studied 77 U.S. South Asians — 44 with diabetes and 33 without — on their dietary...
DIABETES type 2 symptoms include weight loss, feeling very tired, and feeling thirsty all the time. But, you could lower your risk of high blood sugar by adding this cheap fruit to your diet everyday, a nutritionist has claimed.
Conclusion: Baicalin decreases sympathetic activity by inhibiting the P2Y12 receptor in stellate ganglia satellite glial cells to maintain the balance between sympathetic and parasympathetic nerves and relieves DCAN in the rat.Cell Physiol Biochem 2018;46:986 –998
Conclusion: Collectively, our results show that palmitate induces CCL4 expression via activation of the TLR4-MyD88/NF-kB/MAPK/ PI3K signaling cascade. Thus, our findings suggest that the palmitate-induced CCL4 production might be an underlying mechanism of metabolic inflammation.Cell Physiol Biochem 2018;46:953 –964
CONCLUSIONS These results strongly suggest that liraglutide is able to enhance autophagy and promote pancreatic β cell proliferation. This study improves our insights into the mechanism by which liraglutide treatment relieves diabetes, and provides experimental evidence for clinical utilization of liraglutide in type 2 diabetes treatment. PMID: 29664069 [PubMed - in process]