Development of a contaminated ischemic porcine wound model and the evaluation of bromelain based enzymatic debridement

Conclusions Our model simulates the initial phase of chronic wounds characterized by a contaminated necrotic eschar allowing evaluation of wound debriding agents, and that a bromelain-based debriding agent completely debrides the contaminated necrotic eschars within one week in this model.
Source: Burns - Category: Dermatology Source Type: research

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ConclusionsOur model simulates the initial phase of chronic wounds characterized by a contaminated necrotic eschar allowing evaluation of wound debriding agents, and that a bromelain-based debriding agent completely debrides the contaminated necrotic eschars within one week in this model.
Source: Burns - Category: Dermatology Source Type: research
Publication date: Available online 9 March 2018 Source:Microbial Pathogenesis Author(s): Ahmed I. El-Batal, Nawal E. Al-Hazmi, Farag M. Mosallam, Gharieb S. El-Sayyad Mono-dispersed copper nanoparticles (CuNPs) were constructed using cheap polysaccharides (citrus pectin, chitosan, and sodium alginate), and by appropriating aqueous fermented fenugreek powder (FFP) under the action of Pleurotus ostreatus (as reducing and preserving means), through the influence of gamma irradiation. The created CuNPs are described by UV-Vis. spectroscopy TEM, DLS, XRD, and FT-IR. XRD study of the CuNPs confirmed the generation of metallic C...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Conclusions The amphotericin B component of SMAT is degraded within 2days under warm storage. While mafenide was stable over 90 days, the bioactivity of SMAT solution may be lost within 2days as well.
Source: Burns - Category: Dermatology Source Type: research
Conclusions/implications While bismuth subsalicylate, and bismuth tribromophenate unbound to Xeroform® demonstrate antimicrobial activity, it appears that Xeroform® dressings do not. The utility of Xeroform® in burn medicine may relate more to use as an impervious dressing than to antimicrobial effect. Donor sites are clean surgical wounds and clean partial thickness burns may have minimal colonization present. In such circumstances, an inactive and impervious dressing may be all that is necessary to promote wound healing. Graphical abstract
Source: Burns - Category: Dermatology Source Type: research
Authors: Vafi F, Bahramsoltani R, Abdollahi M, Manayi A, Hossein Abdolghaffari A, Samadi N, Amin G, Hassanzadeh G, Jamalifar H, Baeeri M, Heidari M, Khanavi M Abstract OBJECTIVE: Burns are complicated traumatic injuries caused by several physical or chemical factors. Plants with a wide range of secondary metabolites, with valuable properties like antioxidant and anti-inflammatory activities, can be a promising source of wound healing agents. MATERIALS AND METHODS: Effects of hydromethanolic extracts of Lythrum salicaria and Hypericum scabrum, individually and in combination, were assessed in second-degree burn ...
Source: Wounds - Category: Journals (General) Tags: Wounds Source Type: research
Publication date: Available online 26 July 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Filippo Fratini, Giovanni Cilia, Barbara Turchi, Antonio Felicioli Beeswax is the substance that forms the structure of a honeycomb; the bees secrete wax to build the honeycombs where to store honey. Thanks to its rich hydrophobic protective properties, the beeswax is in fact present within cosmetics and body products. Also, beeswax is used in the food industry: as a film to wrap cheese for maturing or as a food additive (E901) to give shine to the products. Exactly as the honey which it contains, beeswax is a...
Source: Asian Pacific Journal of Tropical Medicine - Category: Tropical Medicine Source Type: research
CONCLUSION: The broad-spectrum antimicrobial activity of the wound gel indicates it could become a product alternative to current commercial products. PMID: 27447106 [PubMed - as supplied by publisher]
Source: Wounds - Category: Journals (General) Tags: Wounds Source Type: research
CONCLUSION: The broad-spectrum antimicrobial activity of the wound gel indicates it could become a product alternative to current commercial products. PMID: 27447105 [PubMed - as supplied by publisher]
Source: Wounds - Category: Journals (General) Tags: Wounds Source Type: research
Conclusion There are notable differences in the microbiological isolate and antibiotic resistance patterns between burn patients treated in a GICU compared to a designated BICU. In both units, testing positive for resistant microbiological micro-organisms is significantly associated with longer hospital stay.
Source: Burns - Category: Dermatology Source Type: research
Publication date: Available online 4 March 2016 Source:Journal of the Taiwan Institute of Chemical Engineers Author(s): Wei Shao, Hui Liu, Jimin Wu, Shuxia Wang, Xiufeng Liu, Min Huang, Peng Xu Bacterial cellulose (BC) has been extensively explored as some of the most promising biomaterials for biomedical applications. However, BC does not have intrinsically antibacterial property. In the present study, antibacterial BC-silver sulfadiazine (AgSD) composites were prepared by a simple blend method since AgSD is a topical antibacterial agents used as a topical cream on burns. The prepared composites were characterize...
Source: Journal of the Taiwan Institute of Chemical Engineers - Category: Chemistry Source Type: research
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