1H NMR metabolic signature of cerebrospinal fluid following repetitive lower-limb remote ischemia preconditioning
Conclusion 1H NMR spectra combined with pattern recognition analysis offers a new and promising platform to investigate metabolic signatures in patients treated with RIPC. Our results suggest repetitive RIPC mainly changes energy metabolism and amino-acid metabolism in brain, which provides a potential mechanistic understanding of RIPC-induced tolerance to cerebral ischemia.
Source: Neurochemistry International - Category: Neuroscience Source Type: research
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