Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines

Conclusions We characterized that selenoprotein hierarchy is cell-line specific with conserved features. This analysis should be done prior to any experiments in a novel cell line. General significance We reported a strategy based on complementary methods to evaluate selenoproteome regulation in human cells in culture.
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research