Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) Syndrome and Carcinoid Tumors With/Without NECH: A Clinicopathologic, Radiologic, and Immunomolecular Comparison Study

In this study, we compared clinical, radiologic, histologic, immunohistochemical, and molecular features of DIPNECH and isolated carcinoids with/without NECH. The study population included 151 cases (77 female patients and 74 male patients), 19 with DIPNECH and 132 with carcinoids with/without NECH. None of the cases displayed molecular alterations or anaplastic lymphoma kinase expression. Compared with individuals with carcinoids with/without NECH, patients with DIPNECH were more likely to be female individuals (P
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research

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ConclusionImaging studies may provide clues for diagnosis of non-squamous cell laryngeal lesions. Clinical and imaging findings and previous clinical history should be evaluated together in clinical management of laryngeal lesions.ResumoIntroduçãoO carcinoma de células escamosas é a neoplasia laríngea mais comum, representando aproximadamente 95% de todas as neoplasias malignas da laringe. No entanto, vários outros tumores benignos e malignos, e doenças inflamatórias, podem afetar a laringe.ObjetivoO objetivo deste estudo é analisar os achados clínicos e...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Conclusion: The presence of a trabecular pattern helps to differentiate MCC from other SRBC tumors, and specificity approaches that achieved with immunostaining.
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Original Study Source Type: research
Publication date: Available online 12 September 2018Source: The Annals of Thoracic SurgeryAuthor(s): Thomas H. Shin, Elica Inagaki, Teja Ganta, Kevan Hartshorn, Virginia R. Litle, Kei SuzukiAbstractTumor lysis syndrome (TLS) is a life-threatening complication comprised of hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia attributed to release of intracellular contents. While traditionally associated with leukemia and lymphoma after chemotherapy, it is known to occur in solid malignancies. We herein report a rare case of this syndrome after resection of bulky carcinoid tumor of the lung.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Abstract Tumor lysis syndrome (TLS) is a life-threatening complication comprised of hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia attributed to release of intracellular contents. While traditionally associated with leukemia and lymphoma after chemotherapy, it is known to occur in solid malignancies. We herein report a rare case of this syndrome after resection of bulky carcinoid tumor of the lung. PMID: 30218665 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
ConclusionAlthough the SUVmax of each disease overlapped, PET/CT findings provided useful information for the differential diagnosis of anterior mediastinal masses.
Source: Surgery Today - Category: Surgery Source Type: research
AbstractCancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of the appendix are only 0.08% of all cancers, and the treatment remains controversial. It can present as appendicitis or lump or abscess. Gastrointestinal tuberculosis most commonly involves the ileocecal region. Disruption of the integrity of mucosal barriers and impairment in cell-mediated immunity associated with cancerous growth are known to predispose to bacterial infection. The role of antituberculosis ...
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
1331Objectives: To investigate the role of 18F-FDG PET/CT in the management of bilateral adrenal gland lesions. Methods: Retrospectively collect patients with pathology-proved bilateral adrenal lesions (>2cm in diameter), who also underwent pre-therapy 18F-FDG PET/CT scan between Jan 2013 and Nov 2017. SUVmax of the adrenal lesions and the remote lesions on PET/CT were recorded. P
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Endocrine/Neuroendocrine Posters Source Type: research
1373Objectives: To collect preliminary data on 82-Rb (Rb) uptake in malignant tumors on PET/CT. Methods: The data warehouse of our institution was searched for all patients with a histologically proven, untreated malignancy at the time of cardiac Rb PET/CT since its introduction in October 2008 until August 31, 2015 . Two radiologists reviewed Rb PET/CT images and compared Rb uptake of the dominant lesion (LIS) in each patient to the Rb uptake in the liver (LIV), mediastinum blood pool (MBP), lung (LUN) and subcutaneous fat uptake (SCF). Lesion uptake was scored as 4 (LIS> LIV), 3 (LIV> LIS> MBP), 2 (MBP> LIS&g...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Other Solid Tumors Posters Source Type: research
CONCLUSION: Although all of the appendectomy samples were normal macroscopically, data from this study suggest that all specimens should be sent for routine investigation. KEY WORDS: Appendicitis, Appendectomy, Carcinoid, Mucocele, Endometriosis. PMID: 29339597 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
Conclusion: Jordan is a low-risk area for gastric cancer, but carcinoma occurs at a young age and is associated with gastritis, Helicobacter pylori infection, and intestinal metaplasia in a large proportion of cases. Better strategic health planning and early detection is needed, especially in young patients suffering from gastritis. PMID: 28889157 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
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