Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem

Conclusions: A larger proportion of women whose MBS improved had a Lactobacillus dominant microbiota at enrollment than those who had no improvement during the trial, though this difference was not statistically significant. Larger trials are needed to determine whether vaginal microbiota modify or mediate treatment responses in women with GSM.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research

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Authors: Chen S, Ye M Abstract Mantle cell lymphoma (MCL) is a subtype of B-cell non-Hodgkin lymphoma. Heterogeneous and extensive lymphadenopathy is the most common clinical manifestation. Although skeletal involvement is not uncommon in other types of non-Hodgkin lymphoma, primary bone MCL is rare. The present study reported a case of primary tibia MCL in a 50-year-old male presenting with left tibia pain and a rapidly growing lump. Computed tomography and magnetic resonance imaging scans revealed a progressive lesion in the cortical bone and surrounding soft tissue mass. A positron emission computed tomography s...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Publication date: Available online 22 October 2018Source: Arthroscopy TechniquesAuthor(s): Gun Min Youn, Brittany M. Woodall, Nicholas Elena, Edward C. Shin, Neil Pathare, Patrick J. McGahan, James L. ChenAbstractBone marrow aspirate concentrate is commonly harvested to obtain mesenchymal stem cells, progenitor cells, and growth factors. The iliac crest is the most common donor site for bone marrow harvesting and is associated with donor site morbidity of an additional incision and pain from the harvest. Iliac crest harvesting can be cumbersome because it often requires different patient positioning from the surgical proce...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
A Saint Louis University scientist will use $4.5 million in grant money from the National Institutes of Health for separate studies on the side effects of chemotherapy and those from opioids. Daniela Salvemini, a SLU professor of pharmacology and physiology who focuses on pain research, will use a more than $2.8 million NIH grant to study chemotherapy-induced cognitive impairment (CICI), or so-called "chemo-brain," that can be experienced by cancer patients. CICI is a major neurotoxi c side effect…
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
BLAINVILLE, QC, Oct. 23, 2018 -- (Healthcare Sales &Marketing Network) - Duchesnay Inc., a pharmaceutical company specializing in women's health, announced today that it has submitted a supplemental New Drug Application to the U.S. Food and Drug Administ... Biopharmaceuticals, FDA Duchesnay, Osphena, ospemifene
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Publication date: Available online 22 October 2018Source: The Lancet NeurologyAuthor(s): Tony Kirby
Source: The Lancet Neurology - Category: Neurology Source Type: research
Publication date: Available online 22 October 2018Source: The LancetAuthor(s): Uwe Reuter, Peter J Goadsby, Michel Lanteri-Minet, Shihua Wen, Peggy Hours-Zesiger, Michel D Ferrari, Jan KlattSummaryBackgroundA substantial proportion of patients with migraine does not respond to, or cannot tolerate, oral preventive treatments. Erenumab is a novel CGRP-receptor antibody with preventive efficacy in migraine. We assessed its efficacy and tolerability in patients with episodic migraine in whom previous treatment with two-to-four migraine preventives had been unsuccessful.MethodsLIBERTY was a 12-week, double-blind, placebo-contro...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): J. Cafferkey, M. Skally, C. Finn, S. Donlon, M. Fitzpatrick, K. Burns, K. O'Connell, F. Fitzpatrick, E. Smyth, H. Humphreys
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
ConclusionsIn a cohort of patients with sepsis and severe AKI, female sex was associated with improved survival. The relationship between sex and survival was not altered by menopausal status or RRT intensity.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
Publication date: Available online 22 October 2018Source: The Egyptian Heart JournalAuthor(s): Siva Subramaniyan, Neeraj Pandit, Ranjit Kumar Nath, Ajay Raj, Athar Kamal, Deepankar VatsaAbstractBackgroundIt is well established fact that acute coronary occlusion leads to diastolic dysfunction, followed by systolic dysfunction when myonecrosis occur. It is also proven that primary percutaneous coronary intervention (PPCI) is an excellent therapy for ST elevation myocardial infarction (STEMI) to improve outcomes. However there is a paucity of information on efficacy of PPCI in improving diastolic function. Evaluation of the r...
Source: The Egyptian Heart Journal - Category: Cardiology Source Type: research
The objective of the study was to clarify whether there is a relationship between the presence of headache in young volunteers and the mastication muscle tone. Material and Method. Volunteers aged 18 years who underwent general dental examination, clinical evaluation, and examination using the dual-axis diagnostic system Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) form in the Polish language version participated in the study. On the basis of the examination results, these individuals were divided into three groups according to RDC results. A group of healthy individuals (axis I value 0), a group ...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
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