The OCT-ORION Study: A Randomized Optical Coherence Tomography Study Comparing Resolute Integrity to Biomatrix Drug-Eluting Stent on the Degree of Early Stent Healing and Late Lumen Loss [Coronary Interventions]

Conclusions— Despite having a durable polymer, Resolute Integrity zotarolimus-eluting stent exhibited better strut coverage than BioMatrix NeoFlex Biolimus A9–eluting stent having a biodegradable polymer; both showed similar antiproliferative efficacy. This novel, longitudinal, sequential optical coherence tomography protocol using each patient as own control could achieve conclusive results in small sample size. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01742507.

http://circinterventions.ahajournals.org/cgi/content/short/11/4/e006034?rss=1

Source: Circulation: Cardiovascular Interventions - April 13, 2018 Category: Cardiology Authors: Lee, S. W. L., Tam, F. C. C., Lam, S. C. C., Kong, S.-L., Shea, C. P., Chan, K. K. W., Wong, M. K. L., Chan, M. P. H., Wong, A. Y. T., Yung, A. S. Y., Lam, Y.-M., Zhang, L.-W., Wu, K. K. Y., Mintz, G. S., Maehara, A. Tags: Optical Coherence Tomography (OCT), Catheter-Based Coronary and Valvular Interventions, Percutaneous Coronary Intervention Coronary Interventions Source Type: research