Investigation of Ovatodiolide, a Macrocyclic Diterpenoid, as a potential inhibitor of Oral Cancer Stem-Like Cells Properties via the Inhibition of the JAK2/STAT3/JARID1B Signal Circuit

Conclusion These results demonstrate that Ova effectively suppressed oral tumorigenesis and stemness properties via JAK2/STAT3 signaling. Ova may be considered for future clinical usage. Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research