High-speed 3D imaging of cellular activity in the brain using axially-extended beams and light sheets.

This article describes these approaches and presents a simple model that demonstrates key advantages of axially-extended illumination over point-scanning strategies for high-speed volumetric imaging, including longer integration times per voxel, improved photon efficiency and reduced photodamage.
PMID: 29642044 [PubMed - as supplied by publisher]

Source: Current Opinion in Neurobiology - April 7, 2018 Category: Neurology Authors: Hillman EM, Voleti V, Patel K, Li W, Yu H, Perez-Campos C, Benezra SE, Bruno RM, Galwaduge PT Tags: Curr Opin Neurobiol Source Type: research