Pathogenicity of a variant goose parvovirus from short beak and dwarfism syndrome of Pekin ducks in goose embryos and goslings.

Pathogenicity of a variant goose parvovirus from short beak and dwarfism syndrome of Pekin ducks in goose embryos and goslings. Avian Pathol. 2018 Apr 09;:1-29 Authors: Ning K, Liang T, Wang M, Dong Y, Qu S, Zhang D Abstract The pathogenicity of a variant goose parvovirus (GPV) isolated from short beak and dwarfism syndrome (SBDS) of Pekin ducks (strain Cherry Valley) in embryonating goose eggs and goslings was investigated. The virus was easily grown in GPV antibody-free goose embryos and caused high mortality and severe lesions of goose embryos, indicating that the variant GPV shares good adaptation and high pathogenicity to embryonated goose eggs similar to the classical GPV. Like the third egg passage virus (strain H) of a classical GPV, the third egg passage virus (strain JS1) of the variant GPV caused Derzsy's disease in 2-day-old goslings with high mortality. The findings suggest that the variant GPV strain, which had specifically adapted to Pekin ducks, still retained high pathogenicity for its original host. The mortality (73.3-80%) caused by the first and third egg passages of the variant GPV was somewhat lower than that (93.3%) caused by the third passage virus of the classical GPV, reflecting the higher pathogenicity of the classical GPV for its original host. These findings are likely to reinforce the importance of surveillance for parvoviruses in different waterfowl species and stimulate further study to elucidate the i...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research