The association between obesity and restless legs syndrome: a systemic review and meta-analysis of observational studies

Restless legs syndrome (RLS; also known as Willis-Ekbom disease), is a common neurological sensorimotor disorder, which is characterized by uncomfortable sensations in the extremities and an urgent need to move one's legs (RP  et al., 2003). The severity of the symptoms range from occurring only occasionally to nightly and severe, with almost total disruption of sleep (Walters, 2003). Large population studies using full diagnostic criteria reported on the prevalence of clinically significant RLS rates of over 5% in wes tern industrial countries, with a lower prevalence in Asian populations (Allen et al., 2005) prevalence increased with age and a women were at higher risk (Symvoulakis et al., 2010). In addition to genetic factors, RLS can be secondary to various medical conditions, such as iron deficiency, rheumatoid arthritis, diabetes, and end-stage renal disease, as well as pregnancy (Bogan and Cheray, 2013).
Source: Journal of Affective Disorders - Category: Neurology Authors: Tags: Review article Source Type: research