Levamisole-Induced Vasculitis Levamisole-Induced Vasculitis
What is levamisole-induced vasculitis? Learn more about this condition and find out how it's best diagnosed and treated.ePlasty, Open Access Journal of Plastic Surgery
ConclusionIn this analysis of French death certificates mentioning GCA, we observed a stable standardized mortality rate between 2005 and 2014. The most frequent associated diseases were cardiovascular diseases and infections.
Authors: Lee SW, Kim DY, Ahn SH, Park YB, Han KH, Park JY Abstract OBJECTIVES: We evaluated the laboratory and radiological data on liver and investigate liver fibrosis induced by hepatic manifestation of antineutrophil cytoplasmic antibody-associated vasculitis (AAV) using the aspartate aminotransferase to platelet ratio index (APRI) and an index of fibrosis (FIB-4) in 136 immunosuppressive drug-naïve patients. METHODS: We retrospectively reviewed the medical records of 136 patients with AAV without chronic liver diseases or autoimmune diseases. We collected the laboratory and imaging results. We assessed...
Authors: Li S, Shi R, Tian L, Chen J, Li X, Huang L, Yang Z Abstract BACKGROUND: Kawasaki disease (KD) is an acute systemic vasculitis that predominantly affects children, and it can result in coronary artery lesions. Cyclooxygenase-2 (COX-2) is involved in the conversion of arachidonic acid to prostaglandin H2, an important precursor of several prostaglandins. The aim of this study was to examine the association between COX-2 gene polymorphisms and susceptibility to KD. METHODS: A total of 276 subjects (136 KD and 140 controls) were recruited. The analysis of two single nucleotide polymorphisms rs689466 (-1195...
ConclusionIn this review, we summarized the current knowledge on the clinical features, diagnosis, treatment, and pathogenesis of this disease. We should carefully detect the potential cases of ANCA-related HP and OM in patients with intractable OM, HP, or AAV, and make the optimal treatment plan to avoid long-term neurological complications and irreversible hearing loss. Furthermore, due to an increased possibility of relapse, close follow-up, including a hearing test, ANCA titers, imaging examination, and detection of toxic and side effects of immunosuppressive therapy, are necessary.
ConclusionsIn our case the systemic therapy was much less effective than the intravitreal sustained-release dexamethasone implant (Ozurdex ®) for reducing recurrences and halting disease progression. We believe that recurrent and severe cases could benefit from this addition to the classic treatment armamentarium.
International Journal of Dermatology, EarlyView.
We report a patient with SLE–AAV overlap syndrome diagnosed based on clinical, serologic and biopsy-proven histologic findings who presented with subarachnoid hemorrhage (SAH) secondary to ruptured right anterior cerebral artery aneurysm. To the authors’ knowledge, this is the first reported case of SLE–AAV overlap syndrome diagnosed in a patient with a SAH due to an intracranial aneurysm. Neurologic involvement in patients with SLE–AAV overlap syndrome is uncommon and has not been well-studie d. Clinicians who encounter patients with neurologic signs that present with symptoms and a serologic profi...
This review discusses the conventional treatments for large-vessel vasculitis as well as the potential of new biologic therapies.Rheumatology
CONCLUSION: Our case showed that the immunosuppressed state related to multiple factors such as underlying disease, immunosuppressive therapy and hemodialysis may all have contributed to the development of this neoplastic disorder in our patient. PMID: 30316478 [PubMed - as supplied by publisher]
Authors: Lee JY, Lee EK, Lee HJ, Jeong J, Lee SY, Kim JY PMID: 30311469 [PubMed - in process]