Molecular imaging agents for ultrasound.

Molecular imaging agents for ultrasound. Curr Opin Chem Biol. 2018 Apr 06;45:113-120 Authors: Zlitni A, Gambhir SS Abstract Ultrasound (US) imaging is a safe, sensitive and affordable imaging modality with a wide usage in the clinic. US signal can be further enhanced by using echogenic contrast agents (UCAs) which amplify the US signal. Developments in UCAs which are targeted to sites of disease allow the use of US imaging to provide molecular information. Unfortunately, traditional UCAs are too large to leave the vascular space limiting the application of molecular US to intravascular markers. In this mini review, we highlight the most recent reports on the application of molecular US imaging in the clinic and summarize the latest nanoparticle platforms used to develop nUCAs. We believe that the highlighted technologies will have a great impact on the evolution of the US imaging field. PMID: 29631121 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29631121?dopt=Abstract

Source: Current Opinion in Chemical Biology - April 6, 2018 Category: Biochemistry Authors: Zlitni A, Gambhir SS Tags: Curr Opin Chem Biol Source Type: research