Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?

Oral squamous cell carcinoma (OSCC) is the sixth most common malignancy worldwide (Jemal et al. 2009). It occurs at an annual incidence of approximately 263,000, with a mortality rate of approximately 128,000 per year, and is accompanied by a 5-year survival rate of less than 50% (Jemal et al. 2009) (Vormittag et al. 2009). Despite significant diagnostic and therapeutic advances, the prognosis of patients with OSCC has not improved in the past three decades (Jemal et al. 2009). A major prognostic factor is locoregional relapse, as its diagnosis worsens survival to less than 30% (Gonz ález-García et al.

Source: Journal of Cranio-Maxillofacial Surgery - April 9, 2018 Category: ENT & OMF Authors: Ali-Farid Safi, Martin Kauke, Hendrik Jung, Marco Timmer, Jan Borggrefe, Thorsten Persigehl, Hans-Joachim Nickenig, Max Zinser, David Maintz, Matthias Kreppel, Joachim Z öller Source Type: research