Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil

In conclusion, our data characterized the occurrence of an ongoing triple epidemic caused by DENV, ZIKV and CHIKV in Campo Grande, MS, Brazil. Importantly, the knowledge about dengue or zika severity in co-infected individuals is still unknown, however we provided here, new contributions related to the clinical presentations and laboratorial parameters during DENV and ZIKV infections, in an endemic scenario. Author Contributions Patient recruitment and enrollment: RVC, ELA, TMAS, LSB, JBC, MDF, IHR; Patient Classification: RVC, ELA; Performed the experiments: ELA, TMAS, LSB, JCSA, PCGN; Contributed with reagents and lab support: ELA, FBS, RVC, LMOP, AMBF; Discussion of results: ELA, RVC, FBS, LMOP and Revised and commented on the manuscript: RVC, FBS. Corresponding Author Elzinandes Leal de Azeredo (elzinandes@ioc.fiocruz.br or naideazeredo@gmail.com). Conflict of Interest The authors declare that there is no conflict of interest. Data Availability Statement The data analyzed is not available due ethical restrictions and confidentiality terms. Oswaldo Cruz Foundation Ethic Committee (CAAE 57221416.0.1001.5248). Supporting Information Supplemental Table Demographic and laboratory characteristics of suspected cases according to the type of infection (mono or co-infection) during the triple epidemic occurred in Campo Grande, MS, Brazil during 2016. DENV DENV/ZIKV ZIKV Demographic and laboratory characteristics ...
Source: PLOS Currents Outbreaks - Category: Epidemiology Authors: Source Type: research