Fight Aging! Newsletter, April 9th 2018
This studycounters that notion, and the findings may suggest that many senior citizens remain more cognitively and emotionally intact than commonly believed. "We found that older people have similar ability to make thousands of hippocampal new neurons from progenitor cells as younger people do. We also found equivalent volumes of the hippocampus (a brain structure used for emotion and cognition) across ages. Nevertheless, older individuals had less vascularization and maybe less ability of new neurons to make connections. It is possible that ongoing hippocampal neurogenesis sustains human-specific cognitive function throughout life and that declines may be linked to compromised cognitive-emotional resilience. Human Hippocampal Neurogenesis Persists throughout Aging Healthy aging is crucial in a growing older population. The ability to separate similar memory patterns and recover from stress may depend on adult hippocampal neurogenesis (AHN), which is reported to decline with aging in nonhuman primates and mice. New neurons are generated in the dentate gyrus (DG) of the adult human hippocampus, even after middle age, but the extent to which neurogenesis occurs in humans is highly debated and quantitative studies are scarce. Phylogenetic differences between humans and rodents mandate assessment of the different stages of neuronal maturation in the human DG. For example, striatal neurogenesis is found only in humans, while olfactory bulb neurogene...
Source: Fight Aging! - Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
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