Adenosine and adenosine 5'-triphosphate catabolism in systemic blood as a potential biomarker for doxorubicin cardiotoxicity in an experimental rat model in vivo.

CONCLUSION: Acute cardiotoxicity induced by DOX may be measured by increased breakdown of ATP to AMP in the RBC and also breakdown of adenosine to hypoxanthine and uric acid in plasma. PMID: 29623860 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research