Cross-sectional networks of depressive symptoms before and after antidepressant medication treatment

ConclusionsFindings suggest the effects of SSRIs can be studied using the network approach. The increased connectivity, predictability, and communities at week 8 may be explained by the decrease in depressive symptoms rather than specific effects of SSRIs. Future studies with larger samples and placebo controls are needed to offer insight into the effects of SSRIs.Trial RegistrationThe trials described in this manuscript were funded by the NIMH.Pennsylvania/Vanderbilt study:5 R10 MH55877 (https://projectreporter.nih.gov/project_info_description.cfm?aid=6186633&icde=28344168&ddparam=&ddvalue=&ddsub=&cr=1&csb=default&cs=ASC&MMOpt=).Washington study:R01 MH55502 (https://projectreporter.nih.gov/project_info_description.cfm?aid=2034618&icde=28344217&ddparam=&ddvalue=&ddsub=&cr=5&csb=default&cs=ASC).
Source: Social Psychiatry and Psychiatric Epidemiology - Category: Psychiatry Source Type: research