Protective Effect of Znt7 on High Glucose-Induced Epithelial-to-Mesenchymal Transition in Renal Tubular Epithelial Cells

Conclusion: The present study provides evidence that ZnT7 has a protective effect over EMT of RTECs in DN and suggests that the inhibition of HG-induced EMT may be achieved through the MAPK/ERK and TGF- β/Smad pathways. Thereby, ZnT7 could be a potential target for translation medicine and prevention program in DN.Kidney Blood Press Res 2018;43:500 –512
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research