The effect of dose escalation for large squamous cell carcinomas of the anal canal

ConclusionsThere was no observed difference in OS for dose escalation of anal cancers  >  5 cm in this population-based analysis. Differences in local control and salvage therapy cannot be assessed through the NCDB. Whether dose escalation of large tumors may improve local control and colostomy-free survival remains an important question and is the subject of ongoing trials.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research