Dysphagia and Oral Morbidities in Chemoradiation-Treated Head and Neck Cancer Patients

This study prospectively evaluated relationships between oral morbidities and swallowing ability in head/neck cancer patients following chemoradiation therapy (CRT) and at 3  months following CRT. Thirty patients with confirmed head/neck cancer undergoing chemoradiation were assessed with a battery of swallowing measures and measures of oral morbidities related to chemoradiation (xerostomia, mucositis, pain, taste/smell, oral moisture). All measures were completed at b aseline (within the first week of CRT), at 6 weeks (end of treatment), and at 3 months following chemoradiation. Descriptive and univariate statistics were used to depict change over time in swallowing and each oral morbidity. Correlation analyses evaluated relationships between swallowing functio n and oral morbidities at each time point. Most measures demonstrated significant negative change at 6 weeks with incomplete recovery at 3 months. At 6 weeks, mucositis ratings, xerostomia, and retronasal smell intensity demonstrated significant inverse relationships with swallowing function. In addition, oral moisture levels demonstrated significant positive relationships with swallowing function. At 3 months, mucositis ratings maintained a significant, inverse relationship with swallow function. Taste and both orthonasal and retronasal smell intensity ratings demonstrated inverse relatio nships with measures of swallow function. Swallow functions and oral morbidities deteriorate si...
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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Conclusions: Intensity-modulated radiation with helical tomotherapy achieved respectable locoregional control and overall survival, with acceptable toxicity, in head and neck cancer patients.Oncology
Source: Oncology - Category: Cancer & Oncology Source Type: research
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Source: Oncology - Category: Cancer & Oncology Authors: Tags: Oncology Source Type: research
ConclusionThe presence of oral lesions and the chemotherapeutic regimen were highly associated with nutritional status in older patients with cancer.Clinical relevanceDental professionals should be asked to intervene preventively and per-therapy to optimise oral health status in elderly patients with other cancers than head and neck malignancies.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research
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Publication date: Available online 1 February 2018 Source:British Journal of Oral and Maxillofacial Surgery Author(s): H. Boyes, J. Barraclough, R. Ratansi, S.N. Rogers, A. Kanatas The number of clinical trials that relate to patients with cancer of the head and neck is growing. Patient-reported outcomes, which are rarely the primary outcome, are now an important component, and in this structured review to identify and report the characteristics of the questionnaires that have been used in these trials, we summarise the findings reported. We searched several online databases using the key terms: head and neck oncology, he...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
The effectiveness of thyme honey for the management of treatment-induced xerostomia in head and neck cancer patients: A feasibility randomized control trial. Eur J Oncol Nurs. 2017 Apr;27:1-8 Authors: Charalambous A, Lambrinou E, Katodritis N, Vomvas D, Raftopoulos V, Georgiou M, Paikousis L, Charalambous M Abstract PURPOSE: Radiation-induced xerostomia is one of the most common side effects that head and neck cancer patients experience during and after treatment. Despite the various methods for the prevention and treatment of radiation-induced xerostomia, it remains highly prevalent among patien...
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Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
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