GSE97341 Engineering Patient-Specific Tissue Implants

Contributors : Dvir Tal ; Edri ReuvenSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe developed an approach to engineer completely personalized tissue implants that are based merely on the patient ’s own materials and cells. Here, an omentum is extracted from the patient in a safe, easy and quick procedure. The cells and the ECM materials of the tissue are separated and while the cells are reprogrammed to become pluripotent, the ECM is processed to become a personalized thermoresponsive hyd rogel. The undifferentiated cells are then encapsulated within the hydrogel and efficiently differentiated to cardiomyocytes, neurons, and endothelial cells.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research