Mp28-08 clinicopathologic and genomic evaluation of translocation renal cell carcinoma
Translocation renal cell carcinomas (tRCC) represent 1-5% of all RCCs and are associated with aggressive disease and poor outcomes. tRCCs uniformly contain gene fusions of either transcription factor E3 (TFE3) or transcription factor EB (TFEB) with various partners, or rarely, TFEB amplification. However, given the rarity of these tumors, much remains unknown about other important genomic drivers of this disease.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Daniel E. Nassau, Alejandro Sanchez, Renzo Dinatale, Kyle A. Blum, Mazyar Ghanaat, Sounak Gupta, Maria E. Arcila, Martin H. Voss, Robert J. Motzer, Paul Russo, Jonathan Coleman, Ed Reznik, Victor Reuter, A. Ari Hakimi Tags: Kidney Cancer: Epidemiology & Evaluation/Staging I Source Type: research
More News: Cancer | Cancer & Oncology | Carcinoma | Epidemiology | Genetics | Kidney Cancer | Renal Cell Carcinoma | Translocation | Urology & Nephrology