Mp60-16 hypogonadism is associated with lower sperm morphology and lower live birth rates in men  with unexplained infertility

Sertoli cells thrive in an environment of high testosterone concentrations. Therefore, when subjected to low levels of testosterone, from any cause, abnormal spermatogenesis may occur. We performed a secondary analysis of a large, prospective clinical trial of couples with unexplained infertility to analyze whether sperm quality and pregnancy/live birth (LB) rates were associated with low total testosterone (TT).

Source: The Journal of Urology - April 1, 2018 Category: Urology & Nephrology Authors: JC Trussell, Robert Coward, Nanette Santoro, Christy Stetter, Allen Kunselman, Michael Diamond, Karl Hansen, Stephen Krawetz, Richard Legro, James Smith, Anne Steiner, Pasquale Patrizio, Robert Wild, Esther Eisenberg, Heping Zhang, Mark Lindgren Tags: Infertility: Basic Research & Pathophysiology Source Type: research