Pd49-08 investigating corporal gene expression patterns in ischemic priapism using a berk mouse model

Ischemic priapism is a sustained erection lasting more than 4 hours, and can lead to permanent penile scarring. It is estimated that between 44-90% of priapic episodes lasting more than 24 hours lead to erectile dysfunction (ED). Individuals with hematological disorders, especially those with sickle-cell anemia, are at higher risk of developing priapism. Using sickle transgenic-knockout Berkeley (BERK) mice as our model for sickle-cell anemia, we compared gene expression patterns in the corpora cavernosa between sickle-cell mice and control mice in order to identify genes of interest for future research.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Sexual Function/Dysfunction: Basic Research & Pathophysiology II Source Type: research