Smaller breast cancer detected in women with implants
Although breast implants lowered the cancer detection rate on screening mammography,...Read more on AuntMinnie.comRelated Reading: At high risk for breast cancer? Start screening early What's the best way to follow up breast cancer survivors? FDA issues update on cancer linked to breast implants SABCS: RT complicates breast implant reconstruction MRI adds to cancer detection in women with breast implants
This study showed that ESE-16 exposure leads to the aggregation of acidic vesicles, identified as lysosomes, not accompanied by an induction of autophagy. Therefore, ESE-16 disrupts normal endocytic vesicle maturation likely through the inhibition of the microtubule function.Pharmacology 2018;102:9 –16
Neurofibromatosis type 1 (NF1) is a cancer-predisposing syndrome associated with an increased risk of breast cancer. Cutaneous neurofibromas may decrease the diagnostic feasibility of mammography. We aim at elucidating the feasibility of mammography in patients with NF1 by a retrospective register-based analysis of mammography screening. Finnish women aged 5069 years are invited to mammography screening biannually. The invitations, attendance and diagnostic findings are recorded in the Finnish Mass Screening Registry.
Cutaneous squamous cell carcinoma (SCC) rates are 3-fold greater in men compared to women, with higher mortality rates as well. Whether this gender-linked susceptibility to skin cancer results from differences in estrogen signaling is unclear. A recently identified estrogen receptor (ER) variant known as ER- α36 increases gastric, endometrial, and ER-negative breast cancer growth by expanding the cancer stem cell (CSC) population. We hypothesized that ER-α36 expands the CSC population in cutaneous SCC cells to increase skin tumor growth, such that targeting ER-α36 with the anti-cancer drug icaritin b locks SCC growth.
Conclusions: The study demonstrated a high prevalence of depression in women with female-specific cancer, and the results confirm the relationship between PTSS and depression. In addition, educational level and physical distress were also found to be predictors of depression. Implications for Practice: Screening for depressive symptoms should be a component of routine screening in women with female-specific cancer. Oncology nurses should be aware of the distress symptoms experienced by these women and recognize PTSS in patients who are given a diagnosis of female-specific cancer. Awareness will reduce the multiple ris...
Conclusions: Complementary and alternative medicine use is common among Malaysian patients who are undergoing chemotherapy for breast cancer. However, CAM and non-CAM users reported similar symptom burdens, although single-modality use of MBP is likely associated with a lower symptom burden. Implications for Practice: Nurses should keep abreast of current developments and trends in CAM use. Understanding CAM use and the related symptom burden will allow nurses to initiate open discussion and guide their patients in seeking additional information or referrals for a particular therapy.
Conclusions: Participating in a lifestyle intervention may impose additional burdens on patients with cancer undergoing adjuvant chemotherapy. Despite this, most women experienced participation as beneficial, and importantly, all would recommend that patients in the same situation should participate. Implications for Practice: Healthcare professionals should have the patients’ individual needs in mind when implementing lifestyle interventions, and the timing of lifestyle interventions should be implemented thoughtfully in patients with breast cancer undergoing chemotherapy in an adjuvant setting. Furthermore, th...
Conclusions: The results indicated that the psychoeducational program may be effective in reducing distress, anxiety, and depression and in improving the QOL in breast cancer survivors. Implications for Practice: Psychoeducational programs may be effective and should be considered as part of the survivorship care for breast cancer survivors.
Conclusions: The results point to the importance of partners’ involvement in the decision to undergo preventive mastectomy. Also, important others (relatives, friends, and health caregivers) have an impact on the decision. Implications for Practice: Nurses need to consider cultural aspects of patients considering a decision about whether to undergo preventive mastectomy. Understanding the important others who might influence the decision and including them in the decision process are both essential.
Conclusion: Psychological factors were the most important determinants in delay. The MHSB time was less if those first realizing the symptoms were healthcare professionals. Implications for Practice: Healthcare professionals should direct women to screenings and train them to interpret symptoms correctly.
Conclusion: The results indicate that women with breast cancer have embodied the recovering experience to a new self and have adapted to identify their new bodies. They overcome being a female body with an absent breast(s) by discovering the value of their existence and being free from self-objectification. Implications for Practice: This study contributes to the understanding of the perception of body in long-term breast cancer survivors, which reflects the process of adjusting to the loss of a breast/breasts to reconstructing a new body experience. Health professionals could help and encourage women undergoing a mas...