O8.2. duration of untreated psychosis (dup) is associated with worse response to treatment in antipsychotic na ïve first episode psychosis

DiscussionOur findings support that DUP does not affect the severity of illness at baseline, but modifies the response to treatment and clinical severity after 10 weeks. This finding suggests that longer exposition to psychosis might be involved in biological abnormalities that modulate the response to antipsychotics, which could mediate poor response to treatment.
Source: Schizophrenia Bulletin - Category: Psychiatry Source Type: research